Table 1 Comparison of histological and clinical findings between different groups

From: Primary intestinal T-cell and NK-cell lymphomas: a clinicopathological and molecular study from China focused on type II enteropathy-associated T-cell lymphoma and primary intestinal NK-cell lymphoma

Characteristics

Primary intestinal T-cell and NK-cell lymphoma

Primary intestinal T-cell lymphomaa

 

NK-cell group (n=6)

T-cell group (n=32)

P-valueb

Type II EATL (n=7)

PTCL NOS (n=24)

P-valueb

Gender (male/female)

5/1

19/13

0.383

4/3

15/9

1.000

Age >60 years

0 (0)

7 (22)

0.569

2 (29)

5 (21)

0.642

Abdominal pain

3 (50)

4 (13)

0.063

0 (0)

4 (17)

0.550

Fever

5 (83)

12 (38)

0.071

3 (43)

9 (38)

1.000

Bloody stool

4 (67)

17 (53)

0.672

6 (86)

10 (42)

0.083

Chronic diarrhea

1 (17)

13 (41)

0.383

4 (57)

8 (33)

0.384

Multicentric

3 (50)

16 (50)

1.000

6 (86)

9 (38)

0.037c

Perforation

5 (83)

11 (34)

0.065

5 (71)

6 (25)

0.067

Stage (I–II/III–IV)

5/1

20/12

0.643

7/0

12/12

0.026c

Resection only

3 (50)

9 (28)

0.357

4 (57)

5 (21)

0.150

Non-resection

0 (0)

12 (38)

0.149

1 (14)

10 (42)

0.372

Macroscopic type (ulceration/protruding mass)

4/2

24/8

0.644

5/2

18/6

1.000

Tumor cell size (medium/medium to large)

3/3

10/22

0.392

7/0

14/10

0.066

CD4+

0 (0)

5 (16)

0.570

0 (0)

5 (21)

0.562

CD8+

0 (0)

7 (22)

0.569

5 (71)

2 (8)

0.002c

CD56+

5 (83)

12 (38)

0.071

7 (100)

5 (21)

<0.001c

βF-1+

0 (0)

15 (47)

0.063

4 (57)

11 (46)

0.685

CD5+

0 (0)

3 (9)

1.000

3 (43)

13 (54)

1.000

CD30+

1 (17)

9 (28)

1.000

2 (29)

7 (29)

1.000

Granzyme B+

4 (67)

13 (41)

0.378

3 (43)

10 (42)

1.000

TIA-1+

6 (100)

30 (94)

1.000

7 (100)

22 (92)

1.000

EBER32+

6 (100)

2 (6)

<0.001c

0 (0)

2 (8)

1.000

  1. EATL, enteropathy-associated T-cell lymphoma; PTCL NOS, peripheral T-cell lymphoma not otherwise specified.
  2. aDo not including the one was suspected type I enteropathy-associated T-cell lymphoma.
  3. bFisher's exact test (two-tailed).
  4. cStatistically significant.