Table 1 Radiological and histological characteristics of the 151 stereotactic vacuum-assisted breast biopsies according to the type of atypia: flat epithelial, atypical ductal hypoplasia, and lobular neoplasia
From: All atypia diagnosed at stereotactic vacuum-assisted breast biopsy do not need surgical excision
Radiological and histological characteristics | Flat epithelial atypia (n=24), n | Atypical ductal hyperplasia (n=50), n | Lobular neoplasia (n=14), n | Mixed lesions (n=63), n |
|---|---|---|---|---|
Radiological criteria | ||||
BI-RADSa | ||||
3 | — | 1 | — | — |
4 | 19 | 34 | 13 | 53 |
5 | 5 | 15 | 1 | 10 |
Size/extension of microcalcifications | ||||
One measurable focus | ||||
≤20mm | 15 | 26 | 9 | 42 |
> 20mm | 6 | 11 | — | 9 |
No measurable foci | — | 4 | 2 | 8 |
Not specified | 3 | 9 | 3 | 4 |
Disappearance of calcifications after biopsy | ||||
No | 18 | 33 | 10 | 41 |
Yes | 6 | 15 | 4 | 21 |
Not specified | — | 2 | — | 1 |
Histological criteria calcifications | ||||
Number of cores (median) | ||||
Without calcifications | 7 (0–22) | 6 (0–22) | 10 (0–23) | 7 (0–27) |
With calcifications | 8 (2–16) | 8 (0–15) | 6 (2–8) | 8 (1–25) |
Extension | ||||
Calcifications in ≤33% of cores | 6 | 10 | 6 | 5 |
Calcifications in >33% of cores | 18 | 41 | 8 | 59 |
Topography | ||||
In atypia | 20 | 41 | 5 | 62 |
Out of atypia | 4 | 9 | 9 | 1 |
Atypia | ||||
Number of cores with atypia (median) | 3 (1–7) | 2 (1–17) | 2.5 (1–15) | 6 (2–21) |
Percentage of cores with atypia (median) | 17 (9–100) | 18 (4–100) | 18.7 (4–70) | 42.8 (10–100) |
atypia in ≤33% of cores | 22 | 34 | 10 | 20 |
atypia in>33% of cores | 2 | 17 | 4 | 44 |
Number of foci of atypia (median) | 3 (1–7) | 3 (1–17) | 2.5 (1–15) | 6 (2–37) |
1–5 | 22 | 49 | 10 | 25 |
>5 | 2 | 1 | 4 | 38 |
Size of the largest focus of atypia (median) | 2 (1–6) | 2 (1–7) | 1 (1–15) | 3 (1–12) |
1–3 mm | 17 | 49 | 13 | 40 |
4–10 mm | 7 | 1b | 1 | 22 |
11–15 mm | — | — | — | 1 |
Sum of the sizes of foci of atypia (median) | 5 (1–21) | 5 (1–30) | 2 (1–27) | 11 (2–60) |
1–5 mm | 13 | 32 | 9 | 11 |
6–10 mm | 9 | 12 | 3 | 20 |
11–15 mm | 1 | 3 | 0 | 14 |
>15 mm | 1 | 3 | 2 | 18 |
