Table 1 Clinicopathologic features of granulosa cell tumors

From: Prognostic significance of FOXL2 mutation and mRNA expression in adult and juvenile granulosa cell tumors of the ovary

 

Adult

Juvenile

Total (cases)

34

20

Age (years)

51 (36–69)a

36 (18–39)a

Size (cm)

11 (6–17)a

18 (12–25)a

Histology

 Diffuse

21 (62%)

 

 Trabecular

6 (17%)

 

 Microfollicular

4 (12%)

 

 Watered silk

3 (9%)

 

Mitoses (MF/10 HPF)

5 (4–14)a

12 (6–21)a

Stage

 IA

31/34 (91%)

15/20 (75%)

 IC

3/34 (9%)

2/20 (10%)

 IIIB

 

1/20 (5%)

 IIIC

 

2/20 (10%)

Treatment

 SO

21 (62%)

14 (70%)

 BSO

10 (29%)

6 (30%)

 TAH–BSO

3 (9%)

 

Recurrences

12/29 (41%)

3/13 (23%)

Outcome

 NED

16/29 (56%)

10/13 (77%)

 DOD

0

3/13 (23%)

 DOC

1/29 (3%)

0

  1. BSO, bilateral salpingo-oophorectomy; DOC, dead of unrelated causes; DOD, dead of disease; NED, no evidence of disease; SO, salpingo-oophorectomy; TAH, total abdominal hysterectomy.
  2. a Values are shown as median (interquartile range).
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