Table 4 Scoring system for predicting ALK rearrangements

From: Histologic and cytomorphologic features of ALK-rearranged lung adenocarcinomas

Cytologic features

Predominant histologic subtype

Specimen type

Signet ring cells=3 points

Micropapillary=3 points

Small biopsy=1.5 points

Hepatoid cells=3 points

Papillary=2 points

 
 

Solid=1 point

 
  1. Total scores of 2.5 or more are considered ‘highly probable’ for ALK+ (corresponds to predicted probability of 10%).
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