Table 1 Characteristics of study population at baseline (RRSO)

From: Endometrium is not the primary site of origin of pelvic high-grade serous carcinoma in BRCA1 or BRCA2 mutation carriers

 

BRCA1 (N=201)

BRCA2 (N=114)

Total (N=315)

P value

Age at RRSO, median (range)

42 (30–71)

45 (33–66)

43 (30–71)

<0.00

Previous breast cancer (%)

 Yes

86 (43)

32 (28)

118 (38)

0.01

 No

115 (57)

82 (72)

197 (63)

 

Tamoxifen ever used (%)

 Yes

12 (6)

7 (6)

19 (6)

0.55

 No

155 (77)

93 (82)

248 (79)

 

 Unknown

34 (17)

14 (12)

48 (15)

 
  1. Abbreviation: RRSO, risk-reducing salpingo-oophorectomy.