Table 2 Histologic features of pleuroparenchymal fibroelastosis in restrictive allograft syndrome patients

From: Restrictive allograft syndrome post lung transplantation is characterized by pleuroparenchymal fibroelastosis

Pleural fibrosis

16/16 (100%)

Parenchymal fibroelastosis

15/16 (93.8%)

 Subpleural

14/16 (87.5%)

 Paraseptal

7/16 (43.8%)

 Centrilobular

7/16 (43.8%)

 Parenchymal

5/16 (31.3%)

 Grade of parenchymal fibroelastosis (mean±s.d.)

1.77±1.22

Obliterative bronchiolitis

14/16 (87.5%)

 Within areas of fibroelastosis

9/16 (56.3%)

 Outside areas of fibroelastosis

12/16 (75%)

Diffuse alveolar damage, acute and/or organizing

13/16 (81.3%)

Findings at interface of fibroelastosis with unaffected lung tissue

 Fibroblastic foci

6/16 (37.5%)

 Diffuse alveolar damage

7/16 (43.8%)

Other findings

 Thromboemboli, acute and/or organizing

6/16 (37.5%)

 Acute bronchopneumonia

6/16 (37.5%)

 Areas of nonspecific interstitial pneumonia-like fibrosis

4/16 (25%)

 Microscopic honeycomb change

1/16 (6.3%)