Figure 5
From: Mesothelioma with signet-ring cell features: report of 23 cases
(a) Low-power magnification electron micrograph in which the cells show early formation of intracytoplasmic lumina. The small lumen in the center right (arrow) appears to be filled with microvilli. (b) Signet-ring cell with a single, large intracytoplasmic lumen, which appears to displace the nucleus toward the periphery of the cell. (c) Signet-ring cell with several intracytoplasmic lumina that may coalesce to form a single large intracytoplasmic lumen. (a, × 4000; b, × 4400; c, × 5100).
