Table 3 Immunohistochemical results
From: Mesothelioma with signet-ring cell features: report of 23 cases
Marker | Signet-ring cell mesothelioma | Signet-ring cell carcinoma—lung | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
+Cases/n (%) | Grade of reactivity | +Cases/n (%) | Grade of reactivity | |||||||
1+ | 2+ | 3+ | 4+ | 1+ | 2+ | 3+ | 4+ | |||
Calretinin | 23/23 (100) | 0 | 0 | 5 | 18 | 0/7 (0) | 0 | 0 | 0 | 0 |
Keratin 5/6 | 22/22 (100) | 0 | 2 | 10 | 10 | 0/7 (0) | 0 | 0 | 0 | 0 |
Keratin 7 | 21/21 (100) | 0 | 0 | 0 | 21 | 7/7 (100) | 0 | 0 | 2 | 5 |
Keratin 20 | 0/17 (0) | 0 | 0 | 0 | 0 | 0/7 (0) | 0 | 0 | 0 | 0 |
WT1 protein | 20/22 (91) | 3 | 5 | 7 | 5 | 0/7 (0) | 0 | 0 | 0 | 0 |
Podoplanin | 14/15 (93) | 2 | 2 | 4 | 6 | 0/7 (0) | 0 | 0 | 0 | 0 |
Mesothelin | 13/13 (100) | 0 | 1 | 5 | 7 | 1/7 (14) | 1 | 0 | 0 | 0 |
MOC-31 | 0/22 (0) | 0 | 0 | 0 | 0 | 7/7 (100) | 1 | 1 | 3 | 2 |
CEA | 0/22 (0) | 0 | 0 | 0 | 0 | 7/7 (100) | 0 | 1 | 3 | 3 |
TAG-72 | 0/18 (0) | 0 | 0 | 0 | 0 | 6/7 (86) | 0 | 2 | 2 | 2 |
CD15 | 0/16 (0) | 0 | 0 | 0 | 0 | 5/7 (71) | 1 | 1 | 2 | 1 |
TTF-1 | 0/10 (0) | 0 | 0 | 0 | 0 | 6/7 (86) | 0 | 1 | 1 | 4 |
Napsin A | 0/8 (0) | 0 | 0 | 0 | 0 | 4/4 (100) | 0 | 0 | 1 | 3 |
CDX2 | 0/8 (0) | 0 | 0 | 0 | 0 | 0/7 (0) | 0 | 0 | 0 | 0 |
