Table 1 Results of Aurora-A kinase immunohistochemical staining in various T-cell non-Hodgkin’s lymphomas
From: Differential expression of aurora-A kinase in T-cell lymphomas
T-NHL | Aurora-A by IHC | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Positive cases | % of positive cells Number of cases | Pattern | Staining intensity | ||||||
(overall)n (%) | 0–25% | 25–50% | >50% | Cytoplasmic (% cases) | Nuclear (% cases) | 0 | 1 | 2–3+ | |
Peripheral T-cell lymphoma, NOS | 14/14 (100) | 2 | 4 | 8 | 28.5 | 71.5 | 0 | 6 | 8 |
ALK-positive anaplastic large-cell lymphoma | 13/15 (87%) | 5 | 2 | 6 | 100 | 0 | 0 | 6 | 7 |
Cutaneous anaplastic large-cell lymphoma | 9/13 (69.2) | 4 | 2 | 3 | 0 | 100 | 2 | 2 | 5 |
ALK-negative anaplastic large-cell lymphoma | 15/22 (68) | 3 | 7 | 5 | 33 | 67 | 3 | 8 | 4 |
T-prolymphocytic leukemia | 2/3 (67) | 1 | 1 | 0 | 0 | 100 | 1 | 2 | 0 |
Mycosis fungoides | 4/6 (67) | 0 | 1 | 3 | 0 | 100 | 2 | 3 | 1 |
T-lymphoblastic leukemia/lymphoma | 3/5 (60) | 3 | 0 | 0 | 0 | 100 | 2 | 3 | 0 |
Extranodal NK/T-cell lymphoma, nasal type | 3/6 (50) | 1 | 1 | 1 | 0 | 100 | 3 | 2 | 1 |
Angioimmunoblastic T-cell lymphoma | 3/7 (42.8) | 1 | 1 | 1 | 33.3 | 66.7 | 4 | 2 | 1 |
Subcutaneous panniculitis-like T-cell lymphoma | 1/3 (33.3) | 1 | 0 | 0 | 0 | 100 | 0 | 1 | 0 |
Enteropathy-associated T-cell lymphoma | 1/6 (16.7) | 1 | 0 | 0 | 0 | 100 | 0 | 1 | 0 |
