Table 2 COX regression multivariate analysis including MAP3K7 deletion and established prognostic factors of prostate cancer
Parameter | Factor | HR | 95% CI | P-value |
|---|---|---|---|---|
Gleason | 3+4 vs ≤3+3 | 2.3 | 1.76–3.12 | |
4+3 vs ≤3+3 | 5.5 | 4.01–7.73 | <0.0001 | |
≥4+4 vs ≤3+3 | 7.3 | 4.68–11.14 | ||
pT stage | pT3a vs pT2 | 2 | 1.53–2.49 | |
pT3b vs pT2 | 3.5 | 2.73–4.54 | <0.0001 | |
pT4 vs pT2 | 6.3 | 3.77–10.00 | ||
Surgical margin state | R1 vs R0 | 1.5 | 1.25–1.85 | <0.0001 |
MAP3K7 | Deleted vs not deleted | 1.2 | 1.01–1.53 | 0.0376 |
