Figure 6
Case 6: (a) Multinucleated giant cell showing large collections of intracytoplamic, tubular crystalloids which are located on the right and left sides of the cells. A large number of long microvilli cover the apical portion of the cell membrane (left). (b) Higher magnification showing one of the clusters of tubular crystalloids and the presence of large, long microvilli on the apical surface of the cell. (c) A very high magnification of the tubular crystalloids within the endoplasmic reticulum. A honeycomb pattern is seen in those which appear longitudinally oriented. The crystalloids are limited by a single or multiple layers of pleated membranous structures, often resulting in a target-like configuration (a, × 7500; b × 22 800; c, × 75 000).
