Table 2 MEN-1 pancreatic neuroendocrine tumors measuring ≥3 cm

From: Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors

IHC expression

Alternative lengthening of telomeres phenotype

WHO grade 2 a

Aberrant ATRX and/or DAXX

3/3

3/3

Normal ATRX and DAXX

0/9

1/9

  1. Abbreviations: ATRX, alpha thalassemia/mental retardation X-linked; DAXX, death domain-associated protein; IHC, immunohistochemistry; MEN-1, multiple endocrine neoplasia-1; WHO, World Health Organization.21
  2. aAs compared with WHO grade 1, based on KI67 immunolabeling.
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