Table 1 Patient demographics and its association with mitotic count and recurrence
Variables | N | % | Mitotic count (mean±s.d.) | P-value | 5-year RFP (%) | P-value |
|---|---|---|---|---|---|---|
All patients | 485 | 100 | 5.1±6.8 | |||
Age (years) | 0.002 | 0.320 | ||||
≤65 | 176 | 36 | 4.5±6.7 | 80 | ||
>65 | 309 | 64 | 6.1±6.9 | 84 | ||
Gender | 0.355 | 0.001 | ||||
Female | 306 | 63 | 4.8±6.2 | 87 | ||
Male | 179 | 37 | 5.7±7.7 | 73 | ||
Smoking status | <0.001 | 0.088 | ||||
Never | 72 | 15 | 2.1±2.4 | 90 | ||
Former/current | 413 | 85 | 5.7±7.2 | 81 | ||
Laterality | 0.274 | 0.570 | ||||
Left | 205 | 42 | 5.0±6.9 | 81 | ||
Right | 280 | 58 | 5.2±6.7 | 83 | ||
Stage | <0.001 | <0.001 | ||||
IA | 300 | 62 | 4.1±5.6 | 87 | ||
IB | 185 | 38 | 6.8±8.1 | 74 | ||
Pleural invasion | <0.001 | 0.008 | ||||
Absence | 384 | 79 | 4.6±6.2 | 84 | ||
Presence | 101 | 21 | 7.1±8.3 | 75 | ||
Lymphatic invasion | <0.001 | 0.001 | ||||
Absence | 346 | 71 | 4.3±6.0 | 86 | ||
Presence | 139 | 29 | 7.1±8.2 | 74 | ||
Vascular invasion | <0.001 | <0.001 | ||||
Absence | 340 | 70 | 3.6±5.1 | 86 | ||
Presence | 145 | 30 | 8.7±8.7 | 74 | ||
Necrosis | <0.001 | <0.001 | ||||
Absence | 391 | 81 | 3.5±5.0 | 87 | ||
Presence | 94 | 19 | 11.9±8.7 | 62 | ||
Histologic subtype | <0.001 | <0.001 | ||||
AIS/MIA | 9 | 2 | 0.1±0.3 | 100 | ||
Lepidic | 27 | 6 | 1.2±1.4 | 89 | ||
Papillary | 140 | 29 | 3.7±4.9 | 83 | ||
Acinar | 231 | 48 | 4.8±6.5 | 85 | ||
Micropapillary | 12 | 3 | 5.0±3.4 | 64 | ||
Solid | 66 | 14 | 11.6±9.1 | 69 | ||
Architectural grade | <0.001 | <0.001 | ||||
Low | 36 | 7 | 0.9±1.3 | 92 | ||
Intermediate | 371 | 76 | 4.4±6.0 | 84 | ||
High | 78 | 16 | 10.6±8.8 | 68 |
