Figure 3
From: Correlation of DLC1 gene methylation with oncogenic PIK3CA mutations in extramammary Paget's disease
Immunohistochemical analysis of the deleted in liver cancer 1 (DLC1) protein expression in extramammary Paget’s disease. (a) Extramammary Paget’s disease skin pathological section stained with hematoxylin and eosin staining ( × 200). (b) DLC1 protein expression in a normal skin tissue was localized to the cytoplasm ( × 200). (c) DLC1 protein expression in an extramammary Paget’s disease tissue with a 0% methylation level was localized to the cytoplasm ( × 200). (d) DLC1 protein expression was completely undetectable in an extramammary Paget’s disease tissue with 50–80% methylation ( × 200).
