Table 4 Clinical features of T-lymphoblastic lymphoma/leukemia according to PLZF expression
All cases n (%) | PLZF-positive n (%) | PLZF-negative n (%) | P-value | |
|---|---|---|---|---|
Age (yr), median (range) | 25.7 (2–59) | 30.7 (8–57) | 20 (2–59) | |
Age (yr), mean±s.d. | 27.11±15.05 | 30.67±13.21 | 24.37±16.49 | NS |
Age group | NS | |||
Child (⩽15 yr) | 14 /54 (26%) | 5/27 (19%) | 9/27 (33%) | |
Adult (>15 yr) | 40/54 (74%) | 22/27 (82%) | 18/27 (67%) | |
Age >35 yr | 16/54 (30%) | 11/27 (41%) | 5/27 (19%) | 0.074 |
Gender | NS | |||
M | 38/54 (70%) | 21/27 (78%) | 17/27 (63%) | |
F | 16/54 (30%) | 6/27 (22%) | 10/27 (37%) | |
WBC (/μl), median (range, × 1000) | 6200 (1–134) | 5800 (1–134) | 6400 (1.6–105) | |
WBC (/μl), mean±s.d. | 17 585±29 886 | 20 812±36 391 | 14 478±22 191 | NS |
WBC group | ||||
⩾104/μl | 14/53 (26%) | 6/26 (23%) | 8/27 (30%) | NS |
Mediastinal involvement | ||||
Yes | 27/51 (50%) | 11/23 (48%) | 16/31 (52%) | NS |
Bone marrow involvement | ||||
Yes | 32/47 (68%) | 23/24 (96%) | 9/23 (39%) | 0.000 |
Relapse | ||||
Yes | 24/54 (44%) | 13/27 (48%) | 11/27 (41%) | NS |
