Table 3 Deviations (number of categories, see Table 1) from the counted gold standard per observer for nine pathologists estimating tumor cell fraction in lung cancer biopsies and resections
From: The estimation of tumor cell percentage for molecular testing by pathologists is not accurate
Deviation | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Observer number | Mean deviation | Standard deviation | Mean absolute deviation | −7 | −6 | −5 | −4 | −3 | −2 | −1 | 0 | 1 | 2 | 3 | 4 | 5 | 6 |
1 | −0.5319 | 1.89795 | 1.5106 | 0 | 0 | 1 | 2 | 4 | 7 | 9 | 12 | 3 | 7 | 2 | 0 | 0 | 0 |
2 | −2.1489 | 1.38279 | 2.2340 | 0 | 0 | 0 | 9 | 11 | 12 | 10 | 4 | 0 | 1 | 0 | 0 | 0 | 0 |
3 | −2.9574 | 1.96665 | 3.0851 | 2 | 2 | 7 | 7 | 8 | 13 | 3 | 3 | 1 | 1 | 0 | 0 | 0 | 0 |
4 | 1.0426 | 2.42234 | 2.1489 | 0 | 0 | 0 | 0 | 2 | 6 | 8 | 7 | 3 | 4 | 8 | 5 | 4 | 0 |
5 | 1.0000 | 1.92241 | 1.7234 | 0 | 0 | 0 | 0 | 2 | 1 | 9 | 8 | 7 | 9 | 6 | 4 | 1 | 0 |
6 | 1.3191 | 1.54788 | 1.5319 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 13 | 9 | 6 | 10 | 4 | 0 | 0 |
7 | 2.6596 | 1.73552 | 2.7447 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3 | 8 | 12 | 7 | 7 | 8 | 1 |
8 | 1.1277 | 1.84882 | 1.7660 | 0 | 0 | 0 | 0 | 0 | 3 | 9 | 5 | 9 | 12 | 2 | 6 | 1 | 0 |
9 | −0.2128 | 1.92169 | 1.5745 | 0 | 1 | 0 | 1 | 3 | 5 | 13 | 3 | 13 | 5 | 3 | 0 | 0 | 0 |
Total | 0.1442 | 2.50790 | 2.0355 | 2 | 3 | 8 | 19 | 30 | 48 | 66 | 58 | 53 | 57 | 38 | 26 | 14 | 1 |
