Table 5 Multivariable Cox models for renal outcomes

From: Using the Oxford classification of IgA nephropathy to predict long-term outcomes of Henoch–Schönlein purpura nephritis in adults

Variables

Model 1

Model 2

Model 3

 

Hazard ratio (95% confidence interval)

P-value

Hazard ratio (95% confidence interval)

P-value

Hazard ratio (95% confidence interval)

P-value

Proteinuria (1 g/day)

1.16 (0.86–1.57)

0.134

0.89 (0.65–1.24)

0.497

0.94 (0.68–1.31)

0.716

Hypertension (vs no)

3.54 (0.52–23.92)

0.195

6.70 (0.75–60.23)

0.090

2.30 (0.18–29.40)

0.522

Estimated glomerular filtration rate (1 ml/min per 1.73 m2)

1.03 (0.99–1.06)

0.134

1.04 (1.00–1.08)

0.037

1.03 (0.99–1.07)

0.144

Crescents ≥50% (vs<50%)

3.51 (0.92–13.32)

0.065

 

-

3.27 (0.76–14.01)

0.111

Endocapillary hypercellularity (E1 vs E0)

-

 

8.92 (1.56–51.16)

0.014

8.91 (1.47–53.88)

0.017

Tubular atrophy/interstitial fibrosis (T1/2 vs T0)

-

 

10.66 (1.70–66.73)

0.011

8.74 (1.40–54.38)

0.020

  1. Model 1: adjusted for proteinuria, hypertension, estimated glomerular filtration rate, and crescents.
  2. Model 2: adjusted for proteinuria, hypertension, estimated glomerular filtration rate, endocapillary hypercellularity, and tubular atrophy/interstitial fibrosis.
  3. Model 3: adjusted for proteinuria, hypertension, estimated glomerular filtration rate, crescents, endocapillary hypercellularity, and tubular atrophy/interstitial fibrosis.
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