Figure 6
From: Retinoblastoma gene mutations detected by whole exome sequencing of Merkel cell carcinoma
Combined allele frequency for all Merkel cell carcinoma cases. The frequency of retinoblastoma gene (RB1) non-single-nucleotide polymorphisms occurs around 85%. Other retinoblastoma pathway genes occur at lower allelic frequencies, including RBL1 (around 45%) and RBL2 (around 35%).
