Table 1 Clinicopathologic characteristics and fusion partners of ALK-rearranged renal cell carcinomas

From: Reply to ‘Distinct ALK-rearranged and VCL-negative papillary renal cell carcinoma variants in two adults without sickle cell trait’

Study

Number of cases studied

ALK-rearranged cases

  

#

Patient’s age and sex

Patient’s ethnicity

Stage of disease

Tumor morphology

Fusion partner

Follow-up

Debelenko et al1

6

1

16 Years, M

African-American

III

Unclassifieda

VCL

9 Months, NED

Mariño-Enríquez et al2

1

1

6 Years, M

African-American

II

Medullarya

VCL

21 Months, NED

Sugawara et al4

343

2

36 Years, F

Japanese

I

Unclassified

TPM3

2 Years, NED

   

53 Years, F

Japanese

I

Papillary type 2A

EML4

3 Years, NED

Sukov et al5

534

2

61 Years, M

Unknown

I

Papillary

Unknown, not VCL

4 Years, DOD

   

59 Years, M

Unknown

I

Papillary

Unknown, not VCL

1.4 Years, DOD

Total

884

6 (0.7%)

      
  1. DOD, died of disease; F, female; M, male; NED, no evidence of disease.
  2. aRetrospective analysis indicates similar morphology of the tumors.
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