Figure 1
From: Peutz-Jeghers syndrome: a critical look at colonic Peutz-Jeghers polyps

Peutz-Jeghers polyps. Low-power view of a Peutz-Jeghers polyp demonstrating the lobular pattern of organization of the crypts (a). A desmin immunostain shows well-circumscribed aggregates of crypts surrounded by smooth muscle fibers (b). Another Peutz-Jeghers polyp with a lobulated pattern of organization of the crypts (c) and the corresponding immunohistochemical stain for desmin (d). The lobular pattern in this Peutz-Jeghers polyp is less distinct (e). However, a desmin stain uncovers the lobular pattern (f).