Figure 1
From: Endometriosis involving the mucosa of the intestinal tract: a clinicopathologic study of 15 cases
(a) Endometriosis involving colonic mucosa in a biopsy specimen. Endometrioid glands are surrounded by endometrial-type stroma with hemorrhage and edematous changes (H&E, 40 × ). (b) Higher power view of (a), demonstrating hemosiderin-laden macrophages within the stroma (also see inset). The gland on the left is lined by columnar epithelium with pseudostratification and cilia (H&E, 200 × ). (c) Tubal (ciliated) metaplasia (also see inset) (H&E, 200 × ). (d) Squamous metaplasia (H&E, 200 × ). (e) Hybrid gland between colonic mucinous epithelium and endometrial-type epithelium (H&E, 400 × ). (f) Immunostain for CK7 (red) and ER (brown) confirms the presence of the hybrid gland (CK7/ER double immunoperoxidase stain, 40 × ). (g) Replacement of surface epithelium by endometrial-type epithelium (H&E, 40 × ). (h) The endometrial-type surface epithelium was highlighted by CK7 (red) and ER (brown) immunostains (CK7/ER double immunoperoxidase stain, 40X).
