Table 1 Classification of focal cortical dysplasia for the current study using ILAE classification19 and a variation of Palmini et al20 classification

From: The pathology of magnetic-resonance-imaging-negative epilepsy

FCD type

Criteria

ILAE Ia

Isolated lesions presenting as radial dyslamination of neocortex

ILAE Ib

Isolated lesions presenting as tangential dyslamination of neocortex

ILAE Ic

Isolated lesions presenting as both radial and tangential dyslamination

ILAE IIa

Isolated lesion characterized by cortical dyslamination and dysmorphic neurons without balloon cells

ILAE IIb

Isolated lesion characterized by cortical dyslamination and dysmorphic neurons with balloon cells

ILAE IIIa

Occurs in combination with hippocampal sclerosis

ILAE IIIb

Occurs with epilepsy-associated tumors

ILAE IIIc

Adjacent to vascular malformations

ILAE IIId

In association with epileptogenic lesions acquired in early life (ie, traumatic injury, ischemic injury, or encephalitis)

Palmini IA

Isolated architectural abnormalities (dyslamination, accompanied or not by other abnormalities of mild malformation of cortical development, or malformation of cortical development)

Palmini IB

Architectural abnormalities, plus giant or immature, but not dysmorphic, neurons

Palmini IIA

Architectural abnormalities with dysmorphic neurons but without balloon cells

Palmini IIB

Architectural abnormalities with dysmorphic neurons and balloon cells

  1. Abbreviation: ILAE, International League Against Epilepsy.