Table 2 Progression of disease

From: Absence of terminal deoxynucleotidyl transferase expression identifies a subset of high-risk adult T-lymphoblastic leukemia/lymphoma

Parameter

Total

Disease progressed, n (%)

3-Year progression, %

P-valuea

P-valueb (multivariate)

All patients

59

22 (37.3)

39

  

Age (years)

   

0.81

0.50

 >35

24

9 (37.5)

39

  

 ≤35

35

13 (37.1)

39

  

Gender

   

0.31

0.43

 Male

41

17 (41.5)

43

  

 Female

18

5 (27.8)

31

  

Initial disease site

   

0.07

0.40

 Extramedullary

37

10 (27.0)

32

  

 Leukemia

22

12 (54.5)

50

  

WBC

   

<0.0001

0.006

 >100 K/μl

12

11 (91.7)

92

  

 <100 K/μl

47

11 (23.4)

23

  

CNS

   

0.003

0.21

 Positive

11

8 (72.7)

76

  

 Negative

48

14 (29.2)

30

  

ETP

   

0.0002

0.30

 Yes

9

7 (77.8)

87

  

 No

48

15 (31.3)

32

  

 Unknown

2

    

TdT

   

<0.0001

0.0001

 Negative

7

6 (85.7)

86

  

 Positive

52

16 (30.8)

32

  

Karyotype

   

0.09

 

 Abnormal

22

12 (54.5)

60

  

 Diploid

21

7 (33.3)

31

  

 Unknown

16

    
  1. aLog-rank test.
  2. bWald χ2 test (Cox proportional hazards model).