Table 2 Progression of disease
Parameter | Total | Disease progressed, n (%) | 3-Year progression, % | P-valuea | P-valueb (multivariate) |
|---|---|---|---|---|---|
All patients | 59 | 22 (37.3) | 39 | ||
Age (years) | 0.81 | 0.50 | |||
>35 | 24 | 9 (37.5) | 39 | ||
≤35 | 35 | 13 (37.1) | 39 | ||
Gender | 0.31 | 0.43 | |||
Male | 41 | 17 (41.5) | 43 | ||
Female | 18 | 5 (27.8) | 31 | ||
Initial disease site | 0.07 | 0.40 | |||
Extramedullary | 37 | 10 (27.0) | 32 | ||
Leukemia | 22 | 12 (54.5) | 50 | ||
WBC | <0.0001 | 0.006 | |||
>100 K/μl | 12 | 11 (91.7) | 92 | ||
<100 K/μl | 47 | 11 (23.4) | 23 | ||
CNS | 0.003 | 0.21 | |||
Positive | 11 | 8 (72.7) | 76 | ||
Negative | 48 | 14 (29.2) | 30 | ||
ETP | 0.0002 | 0.30 | |||
Yes | 9 | 7 (77.8) | 87 | ||
No | 48 | 15 (31.3) | 32 | ||
Unknown | 2 | ||||
TdT | <0.0001 | 0.0001 | |||
Negative | 7 | 6 (85.7) | 86 | ||
Positive | 52 | 16 (30.8) | 32 | ||
Karyotype | 0.09 | ||||
Abnormal | 22 | 12 (54.5) | 60 | ||
Diploid | 21 | 7 (33.3) | 31 | ||
Unknown | 16 |