Table 1 Previously published studies that have failed to detect KRAS mutations in GISTs
Study | Country | No. of tumors | Mutation detection method |
---|---|---|---|
Agaimy et al15 | Germany, Switzerland | 69 (49 patients) | Nested PCR Sanger sequencing |
Martinho et al16 | Portugal | 26 | Standard PCR Single strand conformation polymorphism |
Daniels et al17 | Germany, The Netherlands | 78 | Multiplex PCR Single nucleotide probe extension assay |
Origone et al18 | Italy | 81 | Nested PCR Sanger sequencing |