Table 1 Previously published studies that have failed to detect KRAS mutations in GISTs

From: No KRAS mutations found in gastrointestinal stromal tumors (GISTs): molecular genetic study of 514 cases

Study

Country

No. of tumors

Mutation detection method

Agaimy et al15

Germany, Switzerland

69 (49 patients)

Nested PCR

Sanger sequencing

Martinho et al16

Portugal

26

Standard PCR

Single strand conformation polymorphism

Daniels et al17

Germany, The Netherlands

78

Multiplex PCR

Single nucleotide probe extension assay

Origone et al18

Italy

81

Nested PCR

Sanger sequencing