Table 1 Clinicopathological characteristics of renal cell carcinomas with angioleiomyoma-like stroma

Patient	Tumor	Age	Gender	Size	Stage	Side	Grade	3p FISH	Trisomy 7 or 17	Follow-up months	Follow-up status	Cystic	Cytoplasm	Two-cell layer pattern	Papillary structures	Branched tubules	Smooth muscle involves fat	Entrapped non-neoplastic tubules	Blood vessels	Calcification	Ossification
1	1	76	M	3.5	T1a	R	2	No deletion	NA	58	NEM, urothelial CA with liver mets	5%	C, FL	Yes	1+	Yes	Yes	No	Thick, slit-like, hemangioma-like	No	No
2	2	78	M	2.8	T1a	R	3	No deletion	No	NA	NA	40%	C, FL	Yes	No	No	Yes	Yes	Thick, slit-like	No	Yes
3	3	73	F	3.0	T1a	L	2	No deletion	No	NA	NA	No	C, FL	Yes	No	No	Yes	Yes	Thick, slit-like	No	No
4	4	59	M	2.8	T1a	R	3	No deletion	No	4	Contralateral tumor (no. 4) resected at 4 months	30%	C, E, FL	Yes	2+	Yes	Yes	Yes	Slit-like	No	Yes
4	5	60		1.8	T1a	L	3	No deletion	No	NA	NA	No	C, E, FL	Yes	2+	Yes	Yes	Yes	Thick, slit-like	No	Yes
5	6	66	F	2.7	T1a	R	2	No deletion	No	2	NED	5%	C, FL	Yes	2+	Yes	Yes	Yes	Thick, slit-like	Yes	Yes
6	7	68	M	2.4	T1a	R	2	No deletion	No	NA	NA	No	C, E, FL	Yes	1+	Yes	Yes	Yes	Slit-like	Yes	No
7	8	76	F	2.2	T1a	L	2	No deletion	No	NA	Identified at autopsy	No	C, FL	Yes	No	No	No	Yes	Thick, slit-like	No	No
8	9	45	F	1.8	T1a	L	2	NA	NA	NA	NA	No	C, FL	Yes	No	No	Yes	No	Thick, slit-like, hemangioma-like	No	No
9	10	59	M	1.7	T1a	R	2	No deletion	No	NA	NA	No	C, FL	Yes	2+	No	Yes	Yes	Thick, slit-like	No	No
10	11	62	F	1.7	T1a	L	3	No deletion	No	38	NED	No	C, E, FL	Yes	3+	Yes	No	Yes	Slit-like, hemangioma-like	No	No
11	12	41	M	1.0	T1a	Allograft	2	No deletion	No	26	NED	5%	C, FL	Yes	1+	Yes	No	No	Slit-like	No	No

Abbreviations: C, clear cytoplasm; CA, carcinoma; E, eosinophilic cytoplasm; F, female; FL, pale, flocculent cytoplasm; FISH, fluorescence in situ hybridization; L, left; M, male; NA, not available; NED, no evidence of residual, recurrent or metastatic disease; NEM, no evidence of metastatic renal cell carcinoma; R, right.

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