Figure 1

Morphologic findings in TEMPI syndrome. Plasma cell clusters showed prominent cytoplasmic vacuolization in patient A (a), and frayed cytoplasm in patient B (b). All cases showed erythroid hyperplasia and atypia, predominantly nuclear blebbing (c), in the setting of superimposed iron deficiency anemia. Features of chronic myeloproliferative neoplasms are not present, specifically, no megakaryocyte clustering or atypia (d).