Table 4 Selected studies: flat epithelial atypia alone on core biopsy with excision

From: Management of flat epithelial atypia on breast core biopsy may be individualized based on correlation with imaging studies

 

Core biopsies

Excisions

Carcinoma (%)

DCIS

Invasive

Recommendation

Lavoue et al38

60

60

8 (13%)a

6

2

Excision

Guerra-Wallace et al21

39

31

4 (13%)

3

1

Excision

Bianchi et al27

190

190

18 (10%)

NR

NR

Excision

Chivukula et al33

39

35

5 (14%)

3

2

Excision

Noske et al39

43

30

2 (7%)

2

0

Excision

Senetta et al40

41

36

0 (0%)

0

0

Case by case

Ceugnart et al41

63

52

2 (4%)

2

0

Case by case

Biggar et al42

51

51

3 (6%)

2

1

Excision

Khoumais et al43

104

94

10 (11%)

5

5

Excision

Uzoaru et al44

145

95

3 (3%)

1

2

Case by case

Peres et al45

128

95

9 (10%)

5

4

Excision

Villa et al46

142

121

7 (6%)

NR

NR

Case by case

This study

94

73

5 (7%)

3

2

Case by case

Total

1139

963

76 (8%)

32

19

 
  1. Abbreviations: DCIS, ductal carcinoma in situ; Invasive, invasive carcinoma; NR, not reported.
  2. Comparison of upgrade rates in selected studies of flat epithelial atypia on core biopsy (adapted from Verschuur-Maes et al4 to include studies with 30 or more excisions and to include studies from 2010 to 2013).
  3. aPercentages rounded to nearest integer.
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