Table 5 Adjusted hazard ratios of death and progression of ovarian carcinoma and their 95% confidence intervals associated with quantitative matrix metalloproteinase-14 immunostaining

From: Visual and automated assessment of matrix metalloproteinase-14 tissue expression for the evaluation of ovarian cancer prognosis

 

Death

Progression

 

Crude hazard ratios (95% confidence interval)

P

Adjusted hazard ratios a (95% confidence interval)

P

Crude hazard ratios (95% confidence interval)

P

Adjusted hazard ratios a (95% confidence interval)

P

Mean cell number of the highest intensity, quartile 4 vs quartiles 1–3 (n=170)

 Q4

0.63 (0.39–1.02)

0.06

0.82 (0.50–1.33)

0.42

0.60 (0.37–0.95)

0.03

0.75 (0.47–1.21)

0.24

 Q1–Q3

1

1

1

1

Average H-score, quartile 4 vs quartiles 1–3 (n=170)

 Q4

0.60 (0.37–0.96)

0.04

0.80 (0.48–1.33)

0.38

0.54 (0.34–0.87)

0.01

0.72 (0.44–1.18)

0.19

 Q1–Q3

1

1

1

1

Maximal intensity (visual) (n=160)

 2 or 3

0.61 (0.40–0.94)

0.02

0.87 (0.55–1.37)

0.54

0.49 (0.33–0.75)

0.001

0.75 (0.48–1.17)

0.2

 0 or 1

1

1

1

1

  1. aModel was adjusted for grade (low vs high), stage (I–II vs III–IV), histology (serous vs others), age (continuous), and preoperative CA-125 (>442 or ≤442 U/ml (median)).