Table 5 Adjusted hazard ratios of death and progression of ovarian carcinoma and their 95% confidence intervals associated with quantitative matrix metalloproteinase-14 immunostaining
Death | Progression | |||||||
---|---|---|---|---|---|---|---|---|
Crude hazard ratios (95% confidence interval) | P | Adjusted hazard ratios a (95% confidence interval) | P | Crude hazard ratios (95% confidence interval) | P | Adjusted hazard ratios a (95% confidence interval) | P | |
Mean cell number of the highest intensity, quartile 4 vs quartiles 1–3 (n=170) | ||||||||
Q4 | 0.63 (0.39–1.02) | 0.06 | 0.82 (0.50–1.33) | 0.42 | 0.60 (0.37–0.95) | 0.03 | 0.75 (0.47–1.21) | 0.24 |
Q1–Q3 | 1 | — | 1 | — | 1 | — | 1 | — |
Average H-score, quartile 4 vs quartiles 1–3 (n=170) | ||||||||
Q4 | 0.60 (0.37–0.96) | 0.04 | 0.80 (0.48–1.33) | 0.38 | 0.54 (0.34–0.87) | 0.01 | 0.72 (0.44–1.18) | 0.19 |
Q1–Q3 | 1 | — | 1 | — | 1 | — | 1 | — |
Maximal intensity (visual) (n=160) | ||||||||
2 or 3 | 0.61 (0.40–0.94) | 0.02 | 0.87 (0.55–1.37) | 0.54 | 0.49 (0.33–0.75) | 0.001 | 0.75 (0.48–1.17) | 0.2 |
0 or 1 | 1 | — | 1 | — | 1 | — | 1 | — |