Figure 2
From: Familial colorectal cancer type X: genetic profiles and phenotypic features
Hematoxylin and eosin-stained slides from colorectal cancers linked to FCCTX demonstrating (a) dirty necrosis and (b) infiltrative growth in the deep tumor margin. Dirty necrosis is characterized by the presence of large amounts of cell detritus and inflammatory cells within the glandular lumina, whereas the infiltrative growth pattern is characterized by the widespread dissemination of intraepithelial, mainly cytotoxic, T lymphocytes within the tumor tissue. Photo is courtesy of Professor Susanne Holck, Hvidovre Hospital, Denmark.
