Table 3 Association between PTEN protein loss and upgrading from Gleason score 6 on biopsy to radical prostatectomy: Johns Hopkins Hospital and Johns Hopkins Bayview Medical Center

From: PTEN loss is associated with upgrading of prostate cancer from biopsy to radical prostatectomy

Model

Odds ratio (95% confidence interval)

P

Age-adjusted

2.93 (1.08–7.95)

0.034

Multivariable-adjusted Aa

2.81 (1.01–7.82)

0.047

Multivariable-adjusted Bb

3.04 (1.08–8.55)

0.035

  1. aAdditionally adjusted for preoperative PSA (continuous, log-transformed) and clinical stage (binary, T2 or higher).
  2. bAdditionally adjusted for preoperative PSA (continuous, log-transformed), clinical stage (binary, T2 or higher), and race (binary, nonwhite).
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