Figure 1

A schematic figure demonstrating a sentinel lymph node with metastatic melanoma. The number of immunoreactive lymphocytes for each of the immune markers was counted in the 1 × 0.02 mm peritumoral area (green line) at the interface between the tumor and the lymph node parenchyma. The number of immunoreactive lymphocytes for each of the immune markers was counted in the 0.2 mm2 intratumoral area (red box) within the tumor deposit. The example demonstrated is for PD-1+ lymphocytes.