Table 3 Tests results
From: Diagnosis of HPV-driven head and neck cancer with a single test in routine clinical practice
% tumor cells in FFPE (fresh frozen) samples | qRT–PCR | RNAscope HPV-test | p16 IHC | DNA-ISH | |
|---|---|---|---|---|---|
1 | 40 (70) | Negative | Negative | Negative | Negative |
2 | 90 (70) | Negative | Negative | Negative | Negative |
3 | 50 (80) | Negative | Negative | Negative | Negative |
4 | 70 (80) | Negative | positive | positive | Negative |
5 | 60 (80) | Positive (++, HPV16) | Positive | Positive | Positive |
6 | 80 (90) | Positive (+++, HPV33) | Positive | Positive | Negative |
7 | 90 (70) | Negative | Negative | Negative | Negative |
8 | 30 (30) | Negative | Negative | Negative | Negative |
9 | 80 (60) | Positive (+, HPV16) | Positive | Positive | Positive |
10 | 90 (90) | Positive (+++, HPV18) | Positive | Positive | Positive |
11 | 70 (60) | Negative | Negative | Negative | Positive |
12 | 30 (60) | Negative | Negative | Negative | Negative |
13 | 80 (50) | Negative | Negative | Negative | Positive |
14 | 80 (50) | Negative | Negative | Positive | Negative |
15 | 90 (90) | Positive (+++, HPV16) | Positive | Positive | Positive |
16 | 80 (40) | Positive (++, HPV16) | Positive | Positive | Positive |
17 | 70 (80) | Positive (+, HPV16) | Positive | Positive | Positive |
18 | 90 (90) | Negative | Negative | Negative | Negative |
19 | 70 | NA | Positive | Positive | Positive |
20 | 80 | NA | Positive | Positive | Positive |
21 | 80 | NA | Positive | Positive | Positive |
22 | 80 (90) | Negative | Negative | Negative | Negative |
23 | 60 | Negative | Negative | Negative | NA |
24 | 70 | NA | Positive | Positive | Positive |
25 | 80 (80) | Positive (+++, HPV33) | Positive | Positive | Positive |
26 | 70 | Positive (+++, HPV16) | Positive | Positive | Positive |
27 | 60 | Positive (+, HPV 16) | Positive | Positive | Positive |
28 | 70 | Positive (+++, HPV18) | Positive | Positive | NA |
29 | 70 (90) | Negative | Positive | Negative | Positive |
30 | 80 (90) | Negative | Negative | Negative | Negative |
31 | 90 (80) | Positive (+++, HPV16) | Positive | Positive | Positive |
32 | 60 (70) | Positive (+, HPV16) | Positive | Positive | Positive |
33 | 80 (80) | Positive (++, HPV16) | Positive | Positive | Positive |
34 | 70 (80) | Positive (+, HPV 33) | Negative | Positive | Negative |
35 | 70 | NA | Positive | Positive | Positive |
36 | 70 | NA | Positive | Positive | Positive |
37 | 40 (30) | Positive (+, HPV16) | Positive | Positive | Positive |
38 | 90 (90) | Positive (+++, HPV16) | Positive | Positive | Positive |
39 | 80 (90) | Positive (+++, HPV16) | Positive | Positive | Positive |
40 | 60 (80) | Positive (+++, HPV16) | Positive | Positive | Positive |
41 | 80 (70) | Negative | Negative | Negative | Positive |
42 | 70 (90) | Positive (+++, HPV16) | Positive | Positive | Positive |
43 | 80 (50) | Positive (+++, HPV16) | Positive | Positive | Positive |
44 | 70 (80) | Positive (+++, HPV16) | Positive | Positive | Positive |
45 | 50 (70) | Positive (+, HPV16) | Positive | Positive | Positive |
46 | 40 (60) | Positive (+, HPV16) | Positive | Positive | Negative |
47 | 80 (70) | Positive (++, HPV16) | Positive | Positive | Negative |
48 | 40 (60) | Negative | Negative | Negative | Negative |
49 | 60 (90) | Positive (+, HPV16) | Positive | Negative | Negative |
50 | 80 (80) | Positive (++, HPV16) | Negative | Positive | Negative |
