Figure 1 | Modern Pathology

Figure 1

From: Comprehensive screening of alternative lengthening of telomeres phenotype and loss of ATRX expression in sarcomas

Figure 1

An undifferentiated pleomorphic sarcoma (a1) with loss of ATRX (a2) but not DAXX (a3) expression positive for alternative lengthening of telomeres phenotype (a4). A myxofibrosarcoma (b1) with preserved ATRX (b2) and DAXX (b3) expression positive for alternative lengthening of telomeres phenotype (b4). A malignant peripheral nerve sheath tumor (c1) with loss of ATRX expression in the sarcomatous area (c2) but not the neurofibromatous area (c3) positive for alternative lengthening of telomeres phenotype (c4). a1, b1, and c1: hematoxylin and eosin stain; a4, b4, and c4: telomere fluorescence in situ hybridization. Original magnification: a1-3, b1-3, and c1-3: × 200; a4, b4, and c4: × 1000.

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