Table 1 Clinical and pathological information for patients with H3K36me3 stain

From: Loss of histone H3 lysine 36 trimethylation is associated with an increased risk of renal cell carcinoma-specific death

 

H3K36me3-positive (N=1066)

H3K36me3-negative (N=388)

Total (N=1454)

P-value

Tumor size, cm

   

<0.0001

 Mean

5.5

7.4

6.0

 

 Median

4.7

6.8

5.0

 

 Range

(0.5–24.0)

(1.5–29.0)

(0.5–29.0)

 

TNM stage

   

<0.0001

 Missing

2

2

4

 

 1

712 (66.9%)

175 (45.3%)

887 (61.2%)

 

 2

133 (12.5%)

66 (17.1%)

199 (13.7%)

 

 3

214 (20.1%)

140 (36.3%)

354 (24.4%)

 

 4

5 (0.5%)

5 (1.3%)

10 (0.7%)

 

Grade

   

<0.0001

 1

96 (9.0%)

13 (3.4%)

109 (7.5%)

 

 2

536 (50.3%)

119 (30.7%)

655 (45.0%)

 

 3

383 (35.9%)

215 (55.4%)

598 (41.1%)

 

 4

51 (4.8%)

41 (10.6%)

92 (6.3%)

 

Necrosis

   

<0.0001

 No

895 (84.0%)

234 (60.3%)

1129 (77.6%)

 

 Yes

171 (16.0%)

154 (39.7%)

325 (22.4%)

 
  1. Abbreviation: H3K36me3, histone H3 lysine 36 trimethylation.