Table 2 Association of H3K36me3 with renal cell carcinoma-specific survival or progression-free survival, adjusted for age and stratified by SSIGN group
H3K36me3 (positive vs negative) (N=1454a) | RCC-specific survival | Progression-free survival | ||||
|---|---|---|---|---|---|---|
No. of events | H3K36me3-negative hazard ratio (95% confidence interval) | P-value | No. of events | H3K36me3-negative hazard ratio (95% confidence interval) | P-value | |
Adjusted for age | ||||||
SSIGN 0–3 (N=937) | 59 | 1.54 (0.86–2.77) | 0.15 | 97 | 1.46 (0.92–2.32) | 0.11 |
SSIGN 4–7 (N=418) | 172 | 1.42 (1.05–1.91) | 0.02 | 226 | 1.34 (1.03–1.75) | 0.03 |
SSIGN 8+ (N=92) | 63 | 1.04 (0.63–1.70) | 0.88 | 74 | 1.26 (0.80–2.00) | 0.32 |
