Figure 2

(a) Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type measured by immunoblotting. Two high-grade serous ovarian carcinoma (HGSOC#1 and #2) cases were used as a positive control. (b) SMARCA4 overexpression in H1299 non-small cell lung carcinoma and BIN67 small cell carcinoma of the ovary, hypercalcemic type cell lines. Note the upper band in BIN67 cells blotted for SMARCA4 is non-specific. β-Actin is the loading control.