Figure 4 | Modern Pathology

Figure 4

From: Integrated analysis of the genomic instability of PTEN in clinically insignificant and significant prostate cancer

Figure 4

Survival curves of association of biochemical recurrence with PTEN loss. (a) PTEN loss from mate pair sequencing and biochemical recurrence in all cases. Case grouped according to PTEN normal (gray) or loss (black). (b) PTEN loss from mate pair sequencing data and biochemical recurrence in Gleason score 7 and above cases. Case grouped according to PTEN normal (gray) or loss (black). (c) Stratification of PTEN loss and TMPRSS2-ERG fusion (ERG) with biochemical recurrence. Case grouped according to PTEN loss/ERG positive (black solid) PTEN loss/ERG negative (black hashed) PTEN normal/ERG positive (gray solid) PTEN normal/ERG negative (gray hashed).

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