Figure 2 | Modern Pathology

Figure 2

From: Silent subtype 3 pituitary adenomas are not always silent and represent poorly differentiated monomorphous plurihormonal Pit-1 lineage adenomas

Figure 2

Histologic features of silent subtype 3 adenomas. The tumors showed diffuse solid growth (a and b) and consisted of spindle-shaped (b) and epithelioid (b) cells with chromophobic to variably eosinophilic cytoplasm (a and b). The tumor cell nuclei (b) show prominent structures that correspond to spheridia (curved arrows); occasional intranuclear pseudoinclusions (arrows) were also readily identified.

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