Figure 3 | Modern Pathology

Figure 3

From: Loss of switch/sucrose non-fermenting complex protein expression is associated with dedifferentiation in endometrial carcinomas

Figure 3

SMARCB1 (INI1) immunostaining in SMARCB1/SMARCA2-deficient dedifferentiated endometrial carcinomas. (a and b) Case 1 showing FIGO (The International Federation of Gynecology and Obstetrics) grade 1 endometrioid component and undifferentiated component in (a), with a higher magnification of the undifferentiated component in (b). (c and d) Case 1 showing a complete loss of SMARCB1 nuclear staining in the undifferentiated component (with internal stromal positive control) and intact SMARCB1 nuclear staining in the differentiated endometrioid component. (e and f) Case 8 showing SMARCB1-deficient undifferentiated component.

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