Table 1 Clinico-demographic parameters for the five glioblastoma subgroups
ALT | ALTM | TEL | TELM | NDTMM-revised | |
---|---|---|---|---|---|
Total number of cases | 24 | 13 | 51 | 36 | 12 |
Median age (years) | 38 (31.5–60) | 48 (38–65.5) | 60 (54–67) | 64 (58–70.75) | 66.5 (58.9–71.1) |
Median survival (months) | 18* (14.41–21.59] | 7.66 (6.78–8.54] | 11# (9.43–12.57) | 6.05 (5.22–6.88) | 3.7 (2–5.4) |
Surgery only | 0 | 3% (n=2) | 3.5% (n=12) | 2.5% (n=14) | 3% (n=9) |
Surgery+radiotherapy | 17.6% (n=12) | 8% (n=7) | 11% (n=19) | 6% (n=8) | 4.1% (n=3) |
Surgery+radiotherapy+TMZ | 20.3% (n=12) | 10.7% (n=4) | 16.5% (n=20) | 10.5% (n=14) | 0 |
>24 months survival | 29% (n=7) 4 treated with TMZ | 0 | 12% (n=6) all treated with TMZ | 0 | 0 |
Near total/total resection | 79% (n=19) | 77% (n=10) | 80% (n=41) | 45% (n=16) | 75% (n=9) |
Partial resection /biopsy combined no. partial: no. biopsy | 21% (n=5) 5:0 | 23% (n=3) 2:1 | 20% (n=10) 7:3 | 55%§ (n=20) 14:6 | 25% (n=3) 2:1 |
Frontal/temporal location | 71% (n=17) | 100% (n=13) | 57% (n=29) | 53% (n=19) | 83% (n=10) |
Parietal/occipital location | 29% (n=7) | 0 | 41% (n=21) | 42% (n=15) | 13% (n=2) |
Other location | 0 | 0 | 2% (n=1) | 6% (n=2) | 0 |