Figure 6
From: ALK rearrangement and overexpression in epithelioid fibrous histiocytoma
ALK rearrangement in epithelioid fibrous histiocytomas demonstrated by FISH. The tumor cell nuclei show a fused signal pair, and abnormally split red and green signals, indicative of a genomic ALK rearrangement (a). In one case, the 5′ (centromeric) probe was lost in tumor cell nuclei, a pattern consistent with unbalanced ALK rearrangement (b).
