Table 4 Multivariate analysis in GCB DLBCL

From: Evaluation of NF-κB subunit expression and signaling pathway activation demonstrates that p52 expression confers better outcome in germinal center B-cell-like diffuse large B-cell lymphoma in association with CD30 and BCL2 functions

 

HR

95% CI

P-value

Age >60 years

2.228

1.209–4.109

0.01

B symptoms

0.993

0.517–1.907

0.983

Serum LDH elevation

1.582

0.888–2.82

0.119

Stage III/IV

2.31

1.203–4.437

0.012

≥2 Extranodal site involvement

1.862

0.968–3.581

0.063

ECOG ≥2

2.059

1.018–4.166

0.045

p52 expression

0.384

0.092–1.61

0.191

  1. Abbreviations: CI, confidence interval; DLBCL, diffuse large B-cell lymphoma; ECOG, Eastern Cooperative Oncology Group; GCB, germinal center B-cell-like subtype; HR, hazard ratio; LDH, lactate dehydrogenase.
  2. The significance of the bold is p<0.05 (statistically significant).