Figure 3 | Modern Pathology

Figure 3

From: Metanephric adenoma: the utility of immunohistochemical and cytogenetic analyses in differential diagnosis, including solid variant papillary renal cell carcinoma and epithelial-predominant nephroblastoma

Figure 3

Histology and immunohistochemistry of Case B (#37) reclassified as papillary renal cell carcinoma. (a) Acini with intervening edematous stroma. (b) WT1 is negative. (c) AMACR shows cytoplasmic positivity. (d) CD57 is negative. (e) CK7 shows cytoplasmic positivity. (f) Fluorescence in situ hybridization with centromeric probes 7 (red) and 17 (green) showed tumor nuclei containing three red and three green signals demonstrating trisomy of chromosomes 7 and 17.

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