Figure 5 | Modern Pathology

Figure 5

From: Metanephric adenoma: the utility of immunohistochemical and cytogenetic analyses in differential diagnosis, including solid variant papillary renal cell carcinoma and epithelial-predominant nephroblastoma

Figure 5

Histology, immunohistochemistry, and fluorescence in situ hybridization (FISH) of solid variant papillary renal cell carcinoma. (a) Papillary structures and tightly packed acini. (b) WT1 is negative. (c) AMACR shows cytoplasmic positivity. (d) CD57 is negative. (e) CK7 shows cytoplasmic positivity. (f) FISH with centromeric probes 7 (red) and 17 (green) showed tumor nuclei containing three red and three green signals demonstrating trisomy of chromosomes 7 and 17.

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