Figure 1 | Modern Pathology

Figure 1

From: Prognostic value of HMGA2, CDK4, and JUN amplification in well-differentiated and dedifferentiated liposarcomas

Figure 1

Schematic representation of the structure of the HMGA2 gene (12q14.3) and matching fluorescence in situ hybridization (FISH) probes: black solid rectangles represent the five exons. The upper part indicates the locations of BAC clones RP11-30I11 (upstream region of 5′-UTR of HMGA2), RP11-299L9 (5′-UTR and exons 1 and 2 of HMGA2), RP11-23C9 (5′-UTR and exons 1, 2, and 3 of HMGA2), CTC-782I9 (third intron and exon 4 of HMGA2), CTD-2240K5 (exons 4 and 5 and 3′-UTR of HMGA2) and RP11-118B13 (3′-UTR of HMGA2), according to http://genome.ucsc.edu/ (February 2009 release).

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