Table 1 Description of the FISH probes used to characterize MDM2, HMGA2, CDK4, and JUN amplification
BAC clone a | Locus | Chromosomal location a | Position a | Origin |
|---|---|---|---|---|
RP11-797C20 | MDM2 | 12q15 | 69 161 511–69 340 249 | CHORIb |
RP11-30I11 | Telomeric to 5′ region of HMGA2 | 65 892 238–66 063 441 | CHORIb | |
RP11-299L9 | 5′ Region and exons 1 and 2 of HMGA2 | 66 049 805–66 225 867 | CHORIb | |
RP11-23C9 | 5′ Region and exons 1, 2, and 3 of HMGA2 | 12q14.3 | 66 093 846–66 246 663 | CHORIb |
CTC-782I9 | Intron 3 and exon 4 of HMGA2 | 66 235 316–66 355 707 | Invitrogenc | |
CTD-2240K5 | Exons 4 and 5 and 3′ region of HMGA2 | 66 325 027–66 457 979 | Invitrogenc | |
RP11-118B13 | 3′ Region of HMGA2 | 66 358 701–66 502 988 | CHORIb | |
RP11-571M6 | CDK4 | 12q14.1 | 57 999 870–58 211 408 | CHORIb |
RP11-63G10 | JUN | 1p32.1 | 59 246 463–59 249 785 | CHORIb |