Table 2 Clinical and histological features of a series of 116 ALT/WDLPS and DDLPS

From: Prognostic value of HMGA2, CDK4, and JUN amplification in well-differentiated and dedifferentiated liposarcomas

 

ALT/WDLPS, N=68 (%)

DDLPS, N=48 (%)

P, Pearson's exact test

Tumor size (mm)

  

0.6

 <150

17 (25)

16 (33)

 

 ≥150

32 (47)

19 (40)

 

N

  

0.2

 N0

37 (97)

27 (87)

 

 N1

1 (2)

4 (13)

 

M

  

0.2

 M0

35 (97)

26 (87)

 

 M1

1 (3)

4 (13)

 

Multifocality

  

0.4

 No

32 (84)

19 (73)

 

 Yes

6 (16)

7 (27)

 

Primary/recurrence

  

0.07

 Primary

36 (82)

22 (61)

 

 Recurrence

8 (18)

14 (39)

 

Site of tumor

  

<0.001

 Peripheral

33 (56)

8 (19)

 

 Axial

26 (44)

33 (80)

 

Grade a

  

<0.001

 1

46 (96)

3 (9)

 

 2

1 (2)

19 (57)

 

 3

0 (0)

11 (33)

 

Surgery type

  

0.1

 Absence of surgery

2 (6)

4 (13)

 

 Excision

19 (54)

10 (32)

 

 Wide resection

14 (40)

17 (55)

 

Margins

  

0.7

 R0

5 (13)

6 (21)

 

 R1

23 (60)

15 (53)

 

 R2

10 (26)

7 (25)

 

Radiotherapy

  

0.2

 No

30 (86)

22 (69)

 

 Yes

5 (14)

10 (31)

 

Chemotherapy

  

0.02

 No

34 (94)

22 (71)

 

 Yes

2 (6)

9 (29)

 

Complete remission after treatment

  

0.02

 No

4 (9)

11 (33)

 

 Yes

39 (91)

22 (67)

 
  1. Abbreviations: ALT/WDLPS, atypical lipomatous tumor/well-differentiated liposarcoma; DDLPS, dedifferentiated liposarcoma; M0, absence of distant metastasis; M1, distant metastasis; N0, absence of node involvement; N1, positive node involvement; R0, microscopically complete resection; R1, macroscopically complete resection; R2, macroscopically incomplete resection; y, years.
  2. aFrench Sarcoma Grading.