Figure 2 | Modern Pathology

Figure 2

From: Poor outcome of hepatocellular carcinoma with stemness marker under hypoxia: resistance to transarterial chemoembolization

Figure 2

Expression of K19, epithelial cell adhesion molecule (EpCAM), and carbonic anhydrase-IX (CAIX) and patients’ outcome in explanted HCCs with/without TACC (cohort 2, n=85). (a, b) The expression status of K19, EpCAM, and CAIX proteins according to the number of TACC sessions. (c) Correlations between K19, EpCAM, and CAIX protein expression. (d) Time-dependent iAUC analysis for recurrence in comparison between Milan criteria and Milan criteria combined with CAIX protein expression. (e) Kaplan–Meier plot for disease-free survival according to the Milan criteria and CAIX protein expression. (f) Time-dependent iAUC analysis for overall survival in comparison between Milan criteria and Milan criteria combined with CAIX protein expression. (g) Kaplan–Meier plot for overall survival according to Milan criteria and CAIX protein expression. *P<0.05. HCC, hepatocellular carcinoma; iAUC, integrative area under the curve; TACE, transarterial chemoembolization.

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