Table 4 Comparison of ERα, PR (percentage of positively stained nuclei) and HER2 (DAKO scores and FISH) expression in paired samples of eight routinely processed primary breast cancers and their EDTA-treated bone metastases

From: Influence of decalcification procedures on immunohistochemistry and molecular pathology in breast cancer

Sample

Immunohistochemistry

FISH

 

ERα

PR

HER2

HER2

 

P

M

P

M

P

M

P

M

1

100

100

0

20

0

0

  

2

>10a

50

<10a

5

—a

1+

  

3

90

100

50

20

0

0

  

4

>10a

20

<10a

2

—a

2+

Nega

Neg

5

>10a

100

<10a

0

—a

0

  

6

90

100

75

20

0

0

  

7

90

100

90

90

0

0

  

8

>10a

75

>10a

75

+a

3+

Posa

Pos

  1. Abbreviations: M, metastasis; P, primary tumor.
  2. aMaterial not available, information obtained from pathological records.
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