Figure 2 | Modern Pathology

Figure 2

From: Ampullary carcinoma is often of mixed or hybrid histologic type: an analysis of reproducibility and clinical relevance of classification as pancreatobiliary versus intestinal in 232 cases

Figure 2

A case of ampullary carcinoma with morphologic heterogeneity (mixed pancreatobiliary and intestinal features). (a) Glands show mixed morphologic patterns with intestinal-type units (right side of the image) lined by tall columnar cells with pseudostratified nuclei, and more smaller pancreatobiliary glands lined by low cuboidal eosinophilic epithelium with a high nuclear to cytoplasmic ratio, and no nuclear elongation or pseudostratification (center and upper left). (b) Higher power view of the more pancreatobiliary-type glands within the center of the same tumor. (c) Higher power view of the more intestinal glands in the same case.

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